Evans CH, Robbins PD, Ghivizzani SC, Wasko MC, Tomaino MM, Kang R, Muzzonigro TA, Vogt M, Elder EM, Whiteside TL, Watkins SC, Herndon JH. Gene transfer to human joints: progress toward a gene therapy of arthritis. Proceedings of the National Academy of Sciences of the United States of America. 102(24):8698-8703, 2005.

Kang R, Stern PJ. Fracture dislocations of the proximal interphalangeal joint. Journal of the American Society for Surgery of the Hand. 2(2):47-59, 2002.

Kang R, Stern PJ. Humeral nonunion associated with metallosis secondary to use of a titanium flexible humeral intramedullary nail: a case report. Journal of Bone and Joint Surgery. 84-A(12): 2266-2269, 2002.

Bittner JB 4th, Kang R, Stern PJ. Management of flexor tendon sheath ganglia: a cost analysis. Journal of Hand Surgery. 27-A(4): 586-590, 2002.

Kang R. A simple, effective, and convenient method of ring removal. Hand to Hand, Association of Hand Care Professionals. 18(3): 2, 2001.

Kang R, Ghivizzani SC, Muzzonigro TS, Herndon JH, Robbins PD, Evans CH. The Marshall R. Urist Young Investigator Award. Orthopaedic applications of gene therapy: From concept to clinic. Clinical Orthopaedics and Related Research. 375: 324-337, 2000.

Evans CH, Ghivizzani SC, Kang R, Muzzonigro TS, Wasko MC, Herndon JH, Robbins PD. Gene therapy for rheumatic diseases. Arthritis and Rheumatism. 42(1): 1-16, 1999.

Weiss KR, Georgescu HI, Gollin SM, Kang R, Evans CH. Trisomy 7 in synovial fibroblasts obtained from arthritic joints. Inflammation Research. 48(supplement 2): S132-S133, 1999.

Ghivizzani SC, Muzzonigro TS, Kang R, Evans CH, Robbins PD. Clinical gene therapy for arthritis. Drugs Today. 35(4-5): 389-396, 1999.

Ghivizzani SC, Lechman ER, Kang R, Tio C, Kolls J, Evans CH, Robbins PD. Direct adenovirus-mediated gene transfer of interleukin 1 and tumor necrosis factor alpha soluble receptors to rabbit knees with experimental arthritis has local and distal anti-arthritic effects. Proceedings of the National Academy of Sciences of the United States of America. 95(8): 4613-4618, 1998.

Kang R, Marui T, Ghivizzani SC, Nita IM, Georgescu HI, Suh JK, Robbins PD, Evans CH. Ex vivo gene transfer to chondrocytes in full-thickness articular cartilage defects. Osteoarthritis and Cartilage. 5(2): 139-143, 1997.

Kang R, Ghivizzani SC, Herndon JH, Robbins PD, Evans CH. Gene therapy for arthritis: principles and clinical practice. Biochemical Society Transactions. 25(2): 533-537, 1997.

Ghivizzani SC, Kang R, Georgescu HI, Lechman ER, Jaffurs D, Engle JM, Watkins SC, Tindal MH, Suchanek MK, McKenzie LR, Evans CH, Robbins PD. Constitutive intra-articular expression of human IL-1 beta following gene transfer to rabbit synovium produces all major pathologies of human rheumatoid arthritis. Journal of Immunology. 159(7): 3604-3612, 1997.

Watkins SC, Macaulay W, Turner D, Kang R, Rubash HE, Evans CH. Identification of inducible nitric oxide synthase in human macrophages surrounding loosened hip prostheses. American Journal of Pathology. 150(4): 1199-1206, 1997.

Evans CH, Ghivizzani SC, Kang R, Herndon JH, Robbins PD. Progress towards arthritis gene therapies. Rheumatoid Arthritis – ID Research Alert. 1(5): 241-245, 1997.

Gerich TG, Kang R, Fu FH, Robbins PD, Evans CH. Gene transfer to the rabbit patellar tendon: potential for genetic enhancement of tendon and ligament healing. Gene Therapy. 3(12): 1089-1093, 1996.

Evans CH, Robbins PD, Ghivizzani SC, Herndon JH, Kang R, Bahnson AB, Barranger JA, Elders EM, Gay S, Tomaino MM, Wasko MC, Watkins SC, Whiteside TL, Glorioso JC, Lotze MT, Wright TM. Clinical trial to assess the safety, feasibility, and efficacy of transferring a potentially anti-arthritic cytokine gene to human joints with rheumatoid arthritis. Human Gene Therapy. 7(10): 1261-1280, 1996.

Chapters In Press
Ghivizanni SC, Kang R, Evans CH, Robbins PD. Gene therapy for arthritis. In: Concepts in Gene Therapy. Eds: M Strauss, JA Barranger. pp. 413-428. Walter de Fruyter, New York, 1997.

Robbins PD, Ghivizzani SC, Kang R, Jaffurs DC, Evans CH. Development of a gene therapy for arthritis. In: Interdisciplinary Approaches to Gene Therapy: Legal, Ethical, and Scientific Aspects. Eds: S Mueller, J Simon, J Vestig. pp. 41-50. Springer-Verlag, Heidelberg, 1997.

Kang R, Robbins PD, Evans CH. Methods for gene transfer to synovium. In: Methods in Molecular Medicine: Gene Therapy Protocols. Ed: PD Robbins. pp. 357-368. Humana Press Inc., Totowa, New Jersey, 1996.

1) Orthopaedic applications of gene therapy
a) Rheumatoid arthritis
b) Full-thickness articular cartilage defects
c) Tendons, ligaments, and menisci
1994) Trisomy 7 in rheumatoid, osteoarthritic, and normal synovium

1991-1993 Department of Orthopaedic Surgery, Yale University School of Medicine, New Haven, CT

1) Thesis Research: Response of interleukin-3 dependent hematopoietic precursor cell lines to osteoblast-derived cytokines

2) Characterization of a putative new growth factor in media conditioned by mouse helper T-cell clone D10.G4.1
1987-1989 Department of Biology, Dartmouth College, Hanover, NH

Honors Thesis Research: Formation of new synaptic contacts by allotransplants of the superficial flexor muscle nerve in the crayfish

1988 Department of Transplantation, The Jerome H. Holland Laboratory, American Red Cross, Rockville, MD

Suppression of proliferation of responder cells by pre-incubation of stimulator cells with colchicine, cerulinin, cycloheximide, and ammonium chloride in mixed lymphocyte culture

Kang R. Limited open fasciotomy for Dupuytrens contractures. Podium Presentation, Mary S. Stern Fellowship Reunion III. 2006.

Kang R, Kiefhaber T, Stern PJ. Narcotic analgesic use after open carpal tunnel release. Poster Presentation, American Society for Surgery of the Hand, 57th Annual Meeting, 2002.

Kang R, Stern PJ. Approaches to the proximal interphalangeal joint. Video Presentation. 2001.

Muzzonigro TS, Kang R, Herndon JH, Wasko MC, Fitzgerald S, Tomaino MM, Watkins SC, Ghivizzani SC, Robbins PD, Evans CH. Gene therapy for arthritis – A progress report on the first human trial. Podium Presentation, Orthopaedic Research Society, 44th Annual Meeting, 1998.

Weiss KR, Georgescu HI, Gollin SM, Kang R, Evans CH. Trisomy 7 in synovial fibroblasts obtained from arthritic joints. Podium Presentation, American College of Rheumatology 62nd National Scientific Meeting, 1998.

Kang R, Ghivizzani SC, Herndon JH, Bahnson AB, Barranger JA, Elders EM, Maillard R, Tomaino MM, Wasko MC, Robbins PD, Evans CH. Gene transfer to the human rheumatoid joint. Podium Presentation, Orthopaedic Research Society, 43rd Annual Meeting, 1997.

Ghivizzani SC, Kang R, Georgescu HI, Nita IM, Jaffurs D, Engle JM, Watkins SC, Tindal MH, Suchanek MK, McKenzie LR, Evans CH, Robbins PD. Constitutive expression of IL-1 following gene transfer to synovium produces all pathologies of rheumatoid arthritis. Podium Presentation, Orthopaedic Research Society, 43rd Annual Meeting, 1997. Podium Presentation, American College of Rheumatology 60th National Scientific Meeting, 1996.

Kang R, Marui T, Nita IM, Georgescu HI, Suh JK, Robbins PD, Evans CH. Gene therapy for full-thickness articular cartilage defects. Podium Presentation, Orthopaedic Research Society, 42nd Annual Meeting, 1996. Poster Presentation, 7th Congress of the European Society of Sports Traumatology, Knee Surgery, and Arthroscopy, 1996.

Kang R, Fields A, Zamparo J, Horowitz MC. Osteoblast mediated mast cell proliferation. Podium Presentation, Orthopaedic Research Society, 42nd Annual Meeting, 1996.

Gerich TG, Kang R, Georgescu HI, Nita IM, Fu FH, Robbins PD, Evans CH. Comparison of viral vectors of potential use for gene transfer to ligaments and menisci. Poster Presentation, Orthopaedic Research Society, 42nd Annual Meeting, 1996.

Saito M, Kang R, Nita IM, Georgescu HI, Robbins PD, Evans CH. Ex vivo gene therapy for antigen-induced arthritis in the chronic phase in rabbits. Poster Presentation, Orthopaedic Research Society, 42nd Annual Meeting, 1996.

Stefanovic-Racic M, Watkins S, Kang R, Turner D, Evans CH. Identification of inducible nitric oxide synthase in human osteoarthritic cartilage. Poster Presentation, Orthopaedic Research Society, 42nd Annual Meeting, 1996.

Ghivizzani SC, Kang R, Hatton C, Tio C, Lechman ER, Emmert A, Robbins PD, Evans CH. In vivo delivery of genes encoding soluble receptors for IL-1 and TNF- results in a synergistic therapeutic effect in antigen-induced arthritis in the rabbit knee. Podium Presentation, American College of Rheumatology 60th National Scientific Meeting, 1996.

Gerich TG, Kang R, Fu FH, Robbins PD, Evans CH. Gene transfer to ligaments and menisci. A study in rabbits. Plenary Presentation, 109th Annual Meeting of the American Orthopaedic Association, 1996. Podium Presentation, 2nd World Congress on Sports Trauma/American Orthopaedic Society for Sports Medicine 22nd Annual Meeting, 1996. Podium Presentation, Annual Meeting of the Arthroscopy Association of North America, 1996.

Robbins PD, Ghivizzani SC, Kang R, Storkus J, Tahara H, Zitvogel L, Couderc B, Lotze MT, Evans CH. Development of gene therapies for arthritis and cancer. Luneborg Symposium on Interdisciplinary Approaches to Gene Therapy, 1996.

Kang R, Georgescu HI, Nita IM, Robbins PD, Evans CH. Susceptibility of human synovial fibroblasts to retroviral transduction and retransduction with MFG-IRAP. Poster Presentation, 59th National Meeting of the American College of Rheumatology, 1995.

Krause K, Sheldon D, Kang R, Velez SJ. Regeneration of neuromuscular connections after ganglia allotransplants in the crayfish. Poster Presentation, 20th Annual Meeting of the Society for Neuroscience, 1990.

C. Gordon Van Arman Award, Third Place. Trisomy 7 in Synovial Fibroblasts Obtained from Arthritic Joints. Weiss KR, Georgescu HI, Gollin SM, Kang R, Evans CH. Inflammation Research Society 9th International Conference, 1998.

The American Orthopaedic Association-Zimmer Travel Award for Orthopaedic Residents. Activated Macrophages Produce a Nitric Oxide Synthase and Release Nitric Oxide, A Known Regulator of Bone Resorption. Macaulay W, Shanbhag A, Watkins SC, Turner D, Kang R, Stefanovic-Racic M, Rubash HE, Evans CH. 1997.

Best Basic Science Research Paper by a Resident. Gene Therapy for Full Thickness Articular Cartilage Defects – A Feasibility Study. Kang R, Marui T, Ghivizzani SC, Nita IM, Georgescu HI, Suh JK, Robbins PD, Evans CH. Resident/Fellow Research Day, Department of Orthopaedic Surgery, University of Pittsburgh School of Medicine, 1996.

The Eastern Orthopaedic Association Resident/Fellow Award. Gene Therapy for Full Thickness Articular Cartilage Defects – A Feasibility Study. Kang R, Marui T, Ghivizzani SC, Nita IM, Georgescu HI, Suh JK, Robbins PD, Evans CH. 1995.

The American Orthopaedic Association-Zimmer Travel Award, Alternate. Gene Therapy for Full Thickness Articular Cartilage Defects – A Feasibility Study. Kang R, Marui T, Ghivizzani SC, Nita IM, Georgescu HI, Suh JK, Robbins PD, Evans CH. 1995.

Yale University School of Medicine: Alpha Omega Alpha 1993
Research Fellowship 1992

Dartmouth College: A.B. with High Honors in Biology 1989
Magna Cum Laude 1989
Rufus Choate Scholar 1987
Dean’s List 1985-1989

Big Brother of the Year. Big Brothers/Big Sisters of South Central Connecticut. 1991.

Kang R. Prospects for Using Gene Transfer to Treat Osteoarthritis. Current Topics in Rheumatology: Osteoarthritis. North Shore Hospital, Manhasset, NY, 1995.