Clinical Research Trials
Advancing medical understanding

Clinical research allows us to identify the latest and most effective treatments, resulting in improved outcomes for our patients. Peninsula Orthopaedic Associates is involved with several clinical trials. If you are interested in learning more about the clinical trials below, please contact Research Coordinator Lori Short, BSN, at lshort@peninsulaortho.com or (410) 543-7530, ext. 5465.

Currently recruiting participants:

• Cartilage Autograft Implantation System (CAIS) for the Repair of Knee Cartilage Through Cartilage Regeneration
  
  The Cartilage Autograft Implantation System (CAIS) is designed as a single surgical treatment of damaged knee cartilage using the subject's own healthy cartilage obtained from a non-weight or low weight-bearing region. CAIS is indicated for the repair of articular cartilage lesions and osteochondritis dissecans (OCD) of the knee through cartilage regeneration.
  
  
• Evaluation of an Acellular Osteochondral Graft for Cartilage Lssions Pilot Trial (EAGLE Pilot)
  
  The Kensey Nash Corp. Cartilage Repair Device is a bioresorbable scaffold designed to promote repair of knee cartilage and subchondral bone. Subjects with knee cartilage damage meeting eligibility criteria will be randomly assigned to receive treatment with the Cartilage Repair Device or a standard surgical technique called microfracture. The purpose of the study is to evaluate the initial safety and effectiveness of the Cartilage Repair Device compared to microfracture.  Learn more.

Recruiting closed at POA:

• Standard Total Knee Arthroplasty Using Platelet Rich Plasma (PRP)
  
  The purpose of this study is to determine if there is a difference in hemoglobin level between patients undergoing total knee arthroplasty with and without platelet-rich plasma. Learn more.